| The biweekly deal flow update Curated by Zoic Capital. (#2) [subscribe] |
| The deals that we thought were notable from the past two weeks: eNeura: Baltimore-based eNeura will begin marketing migraine treatment device to patients. – BaltimoreSun. A recent device using a noninvasive migraine treatment has recently received $17M in investment. Noninvasive uses of directed energy has been a recent trend that we have seen, especially in diagnosing and treating mental conditions. In addition to migraines, we have seen devices with strong clinical results used in treating depression and cognitive impairment following stroke. Such devices show strong promise as they can have the same efficacy as pharmaceuticals but without the common side effects. |
| JenaValve: A aortic valve implant has recently received $5M in funding. – massdevice. Such a valve implant can significantly improve on current devices and, from a platform perspective can be used for not just this particular function, but many other cardiovascular applications. Such applications can be extremely helpful in surgical situations but also for wound healing. For example, there are many wounds that cannot heal due to lack of blood flow to extremities because of a malfunctioning vein valve. |
| Photonicare wins SPIE startup challenge. – Novus Light. A recent imaging system has been shown to have much higher resolution than ultrasound. Although the initial application seems specific, this is an example of recent advances in imaging that we have seen. An increase in accuracy is important, but we are also intrigued by recent devices that take existing imaging modalities and translate them to magnitudes smaller and cheaper implementations. We are truly interested when such improvement result in the imaging modality being used where it is not currently used at all. |
| JDRF and Cam Med Partner to Develop Flexible Patch Pump for Automated Insulin Delivery Systems – Business Insider. Microfluidic devices have existed in research and development for some time now, and the applications are numerous. This can include drug delivery but also diagnostic applications. For us, we are truly interested in a microfluidic system that advances significantly its core applications over current standard of care, but also has an innovative business model that truly takes advantage of the technology. For example, direct to consumer molecular diagnostics. |
| Articles of interest from the past week: •Inflation Is About to Appear ‘With a Vengeance,’ Paul Tudor Jones Says, and may force the new Federal Reserve chair to accelerate interest-rate hikes. – Bloomberg •Head of BIS calls for clampdown on bitcoin. – Financial Times •VIX at 38 Is Waterloo for the beloved short volatility trade. Of all the harrowing things seen in the stock market Monday, one was a special nightmare for investors in what has become one of the stock market’s favorite strategies. – Bloomberg •Too Clever By Half – Epsilon Theory. The smartest animals on my farm… – Epsilon theory •Can you guess which social interventions work? We describe ten major US social interventions. You have to guess whether they had a positive effect, no effect or a negative effect. – 80,000 Hours •Empower Your Mental Health: The Foundational Guide to Neurohacking. – NEUROHACKER COLLECTIVE •San Francisco Bay Area Experiences Mass Exodus Of Residents. The number of people packing up and moving out of the Bay Area just hit its highest level in more than a decade. – CBS San Fran. •Heart Stents Are Useless for Most Stable Patients. They’re Still Widely Used. – The New York Times •61 Books Nassim Taleb Recommends you Read in his Own Words. – Medium“Thinking in Bets” by Dani Saveker: |
| If you found this newsletter interesting I encourage you to forward it on. If you’ve received this from a friend, please subscribe. Thanks for reading and hope everyone has an enjoyable weekend… Neal Mody |
 Curated by the team at Zoic Capital. |
